Loren’s comments on stroke are correct after regrinding crank. There are many variables that can offset each piston (and tilt). I would think one not discussed is the true position of the pin hole to the outside diameter and ring grooves of the piston that results in one side being proud or effectively “tilt”. This is what the break in period is for during first fire up. As mentioned by sniper, blue printing an engine is done by professional racers and very costly to hold those tighter tolerances.
When I was in school learning the machine trade, we had a project to complete, a V4 cylinder engine. starting point was a rough cast block only. We made the crank, cam, heads, pistons, sleeves, valves, ect…. After each engine in the class was completed, they were graded. All 25 engines ran for a 4 hour min. and they were graded on the tolerances achieved. I also remember about a 4K rpm difference between the examples, though hp was not tested. Some had different sounds, some ran smoother and all had specific characteristics for each example. One of the extra credit points was to install a defective part that would still work for the application with an explanation!
If your engine is free turning, still has enough piston to head clearance, think you will be fine and you don’t have a bent crank?.