I agree w/most of the previous commentary,...under scoreing, "Chevy parts don't fit"; duh! he's a builder?????? (probably would say the same about a flathead 6). And for a few hundred,... if it's a complete 341" go for it.
Know that the DeSotos are smaller and lighter than the Chryslers but larger and heavier than the Dodges. And, probably less popular than either. Check http://www.hothemiheads.com/
The upside is, engines don't take much room. Build a dolly, put a wood frame with a top on it and you have another 30"x30" horizonal surface that you can stack stuff on,..... and it rolls. If in the future, you decide not to use it you should be able to easily recover your money.