After restoring this truck many years ago it had this vibration. I thought then possibly the drive shaft? I recently have made many changes. Replaced transmission with a Borg Warner T5, new differential with 3.73 gear, brand new drive shaft with a double cardan cv u joint. Runs and shifts great, but still vibrates on acceleration. So, I've pretty much narrowed it down to the engine. I can get it to vibrate a little by revving in neutral, but it seems more pronounced when driving. I rebuilt this engine about 30 years ago. We bored it and replaced pistons with new. All other components were in good condition. All new bearings and valve grind of course. It's been so long, I can't remember weighing the pistons, however I'm fairly sure I would have. This truck has not been used hardly at all over the years having racked up only a couple thousand miles. It's not bad enough to warrant a tear down, which is why I'm considering the harmonic balancer. It's a bit of a project to do correctly, but I'm guessing it won't hurt anything? I should have been more articulate about when this happens (rpm, which gears, etc.). I'm fairly sure it does it in all gears. Right now I'm replacing the water pump so, I figured this might be a good time to install a damper?